The Staying Safe Intervention: Preventing HCV among Young Opioid Injectors

Principal Investigators: Pedro Mateu-Gelabert, Honoria Guarino

The growing population of young people who inject drugs (PWID) is at extremely high risk for HCV infection through the use of contaminated injection equipment, yet, to date, no behavioral intervention has been sufficiently potent to produce significant reductions in HCV incidence among PWID. To address this critical public health need, our team developed Staying Safe (Ssafe), an innovative, strengths-based, socio-behavioral HCV prevention intervention found in preliminary research to be highly acceptable and feasible, with strong indications of efficacy. The proposed randomized, controlled trial will assess the effectiveness of the Ssafe intervention in reducing both injection-related HCV/HIV risk behavior and HCV incidence among young adults (ages 18-29) who inject opioids (heroin and/or prescription opioids).

For more information: Abstract

  • About NDRI
          Since 1967, National Development and Research Institutes, Inc. (NDRI), a private, not-for-profit 501(c)(3) organization, has conducted substance use and other bio-behavioral research nationwide and throughout the world.

          Drawing on the expertise of our interdisciplinary professional staff and our partners such as medical centers, treatment and prevention programs, universities, CBOs, industry and government NDRI has advanced public health across diverse populations including high-risk and underserved persons, uniformed services, youth and veterans.

          In addition to its focus on addiction, NDRI, organized under specialized institutes, has generated scientific discoveries associated with infectious diseases (particularly HIV and Hepatitis C), overdose, chronic pain, prevention of cardiovascular disease and cancer, tobacco control and criminal justice.

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